PIPELINE

precision

immunology

We’re building a pipeline of targeted therapeutics and therapy-guiding tests to address unmet need in immune-driven illnesses. Our unique understanding of patient biology, coupled with our approach to therapeutics and therapy-guiding tests, enables us to rapidly deliver potentially life-changing therapies to patients in need.

Critical Illness
(Septic Shock)

Therapeutic Need
  • Coagulation
  • Immunosuppression
  • Inflammation

Chronic Illness

Disease Area
  • Rheumatoid Arthritis
  • Other Inflammatory
Signal Discovery
Data
Access

We acquire and aggregate omics and health record data from a range of patients with a specific disease.

Data
Analysis

We analyze omics and health record data using our proprietary AI and machine learning platform to identify biologically distinct patient subgroups.

Therapeutic
Mapping

We match the pharmacology of possible therapies to the biology of each patient subgroup.

IND
Clinical
Development

patients deserve

personalized
treatment

There is an urgent need for new therapies to treat immune-driven critical and chronic illnesses such as sepsis, acute respiratory distress syndrome (ARDS) and rheumatoid arthritis.

We believe our precision-firstTM therapeutic approach has the potential to have meaningful and immediate patient impact.

References

Liu et al. Hospital Deaths in Patients With Sepsis From 2 Independent Cohorts.
JAMA. 2014; 312(1):90–92. DOI:10.1001/jama.2014.5804

Rubenfeld et al. Hospital Volume and the Outcomes of Mechanical Ventilation.
NEJM. 2006; 355:41-50. DOI: 10.1056/NEJMsa053993

Sung et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021; 71: 209-249. DOI: 10.3322/caac.21660

Global report on the epidemiology and burden of sepsis: current evidence, identifying gaps and future directions. Geneva: World Health Organization; 2020. License: CC BY-NC-SA 3.0 IGO.